Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6

• Main Authors: Yuanyuan Luo (Author), Yuanmei Li (Author), Liwei He (Author), Haitao Tu (Author), Xinfeng Lin (Author), Fengli Zhao (Author), Yusheng Huang (Author), Minyong Wen (Author), Lingjun Wang (Author), Zhongqi Yang (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective Xinyang Tablet (XYT) has emerged as a potential intervention to counter sepsis-induced myocardial dysfunction (SMID) by influencing macrophage autophagy and M2 polarization. This study aimed to unravel the underlying mechanism of XYT in sepsis-induced myocardial dysfunction (SIMD)...