Potential combination topical therapy of anal fissure: development, evaluation, and clinical study†

• Main Authors: Amgad E. Salem (Author), Elham A. Mohamed (Author), Hosam M. Elghadban (Author), Galal M. Abdelghani (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Fag: article
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To treat anal fissure, internal anal sphincterotomy may be associated with surgical risks and incidence of incontinence. Botulinum toxin injection into the anal sphincter is invasive and expensive. Headache and hypotension hindered topical treatment with glyceryl trinitrate. Greater patient complian...