Vitrification of porcine cumulus-oocyte complexes at the germinal vesicle stage does not trigger apoptosis in oocytes and early embryos, but activates anti-apoptotic Bcl-XL gene expression beyond the 4-cell stage

• Main Authors: Tamás SOMFAI (Author), Hiep Thi NGUYEN (Author), Men Thi NGUYEN (Author), Thanh Quang DANG-NGUYEN (Author), Hiroyuki KANEKO (Author), Junko NOGUCHI (Author), Kazuhiro KIKUCHI (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present study was to clarify whether or not our vitrification procedure at the germinal vesicle (GV)-stage triggers the apoptotic cascade in oocytes and subsequent embryos. Immature porcine cumulus-oocyte complexes were either vitrified and warmed (vitrified group) or subjected to cry...