Divergent Regulation of OCT and MATE Drug Transporters by Cadmium Exposure

• Auteurs principaux: Hong Yang (Auteur), Shiwei Zhou (Auteur), Dong Guo (Auteur), Obinna N. Obianom (Auteur), Qing Li (Auteur), Yan Shu (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Coordinated transcellular transport by the uptake via organic cation transporters (OCTs) in concert with the efflux via multidrug and toxin extrusion proteins (MATEs) is an essential system for hepatic and renal drug disposition. Despite their clinical importance, the regulation of OCTs and MATEs re...