Sham surgical embryo transfer affects offspring neurodevelopment and manifestation of hypertensive phenotype in ISIAH rats

• Main Authors: Irina Rozkova (Author), Eugeny Brusentsev (Author), Tatyana Igonina (Author), Diana Ragaeva (Author), Olga Petrova (Author), Maria A. Tikhonova (Author), Anna A. Akopyan (Author), Tamara G. Amstislavskaya (Author), Yegor V. Antonov (Author), Sergey Amstislavsky (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study investigates how surgery during pregnancy, i.e., sham operation associated with embryo transfer, affects hypertensive phenotype in ISIAH rats genetically predisposed to hypertension. ISIAH rats born after maternal surgery at fourth day of pregnancy were compared with naturally conceived co...