Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway

• Main Authors: Ziang Zheng (Author), Xinghan Zhao (Author), Bo Yuan (Author), Shan Jiang (Author), Rushan Yan (Author), Xiaowei Dong (Author), Qijun Yao (Author), Haidong Liang (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Soy isoflavones (SI) is a natural bioactive substance exhibiting beneficial effects on human health. This study aims to elucidate the therapeutic potential of SI in the treatment of osteosarcoma (OS) and to investigate the underlying mechanisms, particularly focusing on mitophagy...