Localization of the cannabinoid CB1 receptor and the 2-AG synthesizing (DAGLα) and degrading (MAGL, FAAH) enzymes in cells expressing the Ca2+-binding proteins calbindin, calretinin and parvalbumin in the adult rat hippocampus

• Main Authors: Patricia eRivera (Author), Sergio eArrabal (Author), Manuel eCifuentes (Author), Jesús M. Grondona (Author), Margarita ePérez-Martín (Author), Leticia eRubio (Author), Antonio eVargas Fuentes (Author), Antonia eSerrano (Author), Francisco Javier ePavon (Author), Juan eSuarez (Author), Fernando eRodríguez de Fonseca (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The retrograde suppression of the synaptic transmission by the endocannabinoid sn-2-arachidonoylglycerol (2-AG) is mediated by the cannabinoid CB1 receptors and requires the elevation of intracellular Ca2+ and the activation of specific 2-AG synthesizing (i.e. DAGLα) enzymes. However, the anatomical...