The role of <it>CACNA1S </it>in predisposition to malignant hyperthermia

• Main Authors: Halsall P Jane (Author), Robinson Rachel L (Author), Morris Andrew (Author), Leo Vincenzo (Author), Ringrose Christopher (Author), Carpenter Danielle (Author), Hopkins Philip M (Author), Shaw Marie-Anne (Author)
• Format: Book
• Published: BMC, 2009-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Malignant hyperthermia (MH) is an inherited pharmacogenetic disorder of skeletal muscle, characterised by an elevated calcium release from the skeletal muscle sarcoplasmic reticulum. The dihydropyridine receptor (DHPR) plays an essen...