Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Simulation of Piperacillin/Tazobactam for Dosing Optimization in Late Elderly Patients with Pneumonia

Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Simulation of Piperacillin/Tazobactam for Dosing Optimization in Late Elderly Patients with Pneumonia

The aim of this study was to develop a population pharmacokinetic model for piperacillin (PIPC)/tazobactam (TAZ) in late elderly patients with pneumonia and to optimize the administration planning by applying pharmacokinetic/pharmacodynamic (PK/PD) criteria. PIPC/TAZ (total dose of 2.25 or 4.5 g) wa...

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Main Authors: Noriyuki Ishihara (Author), Nobuhiro Nishimura (Author), Kazuro Ikawa (Author), Fumi Karino (Author), Kiyotaka Miura (Author), Hiroki Tamaki (Author), Takahisa Yano (Author), Takeshi Isobe (Author), Norifumi Morikawa (Author), Kohji Naora (Author)
Format: Book
Published: MDPI AG, 2020-03-01T00:00:00Z.
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