Assessment of Integration-defective HIV-1 and EIAV Vectors In Vitro and In Vivo

• Main Authors: Scott Ellis (Author), Liang Fong-Wong (Author), Sharifah Iqball (Author), Vinay Thoree (Author), Kyriacos A Mitrophanous (Author), Katie Binley (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The interest in integrase-defective lentiviral vectors (IDLVs) stems from their potential advantage of large cloning capacity and broad cell tropism while avoiding the possibility of insertional mutagenesis. Here, we directly compared the transducing potential of IDLVs based on the equine infectious...