Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus.

• Main Authors: Chad E Mire (Author), Joan B Geisbert (Author), Andrea Marzi (Author), Krystle N Agans (Author), Heinz Feldmann (Author), Thomas W Geisbert (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ebola virus (EBOV) causes severe and often fatal hemorrhagic fever in humans and nonhuman primates (NHPs). Currently, there are no licensed vaccines or therapeutics for human use. Recombinant vesicular stomatitis virus (rVSV)-based vaccine vectors, which encode an EBOV glycoprotein in place of the V...