Conservation of 5-HT1A receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis

• Hauptverfasser: Naozumi eAraragi (Verfasst von), Boris eMlinar (Verfasst von), Gilda eBaccini (Verfasst von), Lise eGutknecht (Verfasst von), Klaus-Peter eLesch (Verfasst von), Renato eCorradetti (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2013-08-01T00:00:00Z.
• Schlagworte: article
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Firing activity of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) is controlled by inhibitory somatodendritic 5-HT1A autoreceptors. This autoinhibitory mechanism is implicated in the etiology of disorders of emotion regulation, such as anxiety disorders and depression, as well as in the...