Conservation of 5-HT1A receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis

• Váldodahkkit: Naozumi eAraragi (Dahkki), Boris eMlinar (Dahkki), Gilda eBaccini (Dahkki), Lise eGutknecht (Dahkki), Klaus-Peter eLesch (Dahkki), Renato eCorradetti (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2013-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Firing activity of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) is controlled by inhibitory somatodendritic 5-HT1A autoreceptors. This autoinhibitory mechanism is implicated in the etiology of disorders of emotion regulation, such as anxiety disorders and depression, as well as in the...