BDNF promotes mouse follicular development and reverses ovarian aging by promoting cell proliferation

• Main Authors: Bin Liu (Author), Yongjie Liu (Author), Shuman Li (Author), Pingping Chen (Author), Jun Zhang (Author), Liping Feng (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Brain-derived neurotrophic factor (BDNF) plays an important role in ovarian function including follicle development and oocyte maturation, and embryonic development. However, whether BDNF treatment can reimpose ovarian aging and impaired fertility remains elusive. In this study,...