miR-21 promotes the fibrotic properties in oral mucosa through targeting PDCD4

• Main Authors: Yi-Wen Liao (Author), Lo-Lin Tsai (Author), Yu-Hsien Lee (Author), Pei-Ling Hsieh (Author), Cheng-Chia Yu (Author), Ming-Yi Lu (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Oral submucous fibrosis (OSF) has been regarded as a premalignant disorder of oral cancer, and myofibroblasts are the main cells that are responsible for pathological fibrosis. Hence, elucidation of the molecular mechanism underlying myofibroblast activation is important to treat...