Effect of the antidiabetic agent pioglitazone on bone metabolism in rats

• Päätekijät: Junkichi Kanda (Tekijä), Nobuo Izumo (Tekijä), Yoshiko Kobayashi (Tekijä), Kenji Onodera (Tekijä), Taketoshi Shimakura (Tekijä), Noriaki Yamamoto (Tekijä), Hideaki E. Takahashi (Tekijä), Hiroyuki Wakabayashi (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2017-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Thiazolidinediones (TZDs) are synthetic peroxisome proliferator-activated receptor gamma (PPARγ) agonists used as therapy for type 2 diabetes. However, clinical studies reported that the therapeutic modulation of PPARγ activity using TZDs may induce negative effects on bone metabolism. This study ai...