Significance and possible causes of hormone receptor expression loss in metastatic breast cancer. Phenotypic evolution of luminal <i>BRCA1</i>-associated breast cancer to triple negative subtype in lung metastasis and PARP inhibition strategy in early-line therapy

• Asıl Yazarlar: A. I. Stukan (Yazar), Z. K. Khachmamuk (Yazar), V. V. Antipova (Yazar), A. V. Dzagashtokova (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: ABV-press, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Current clinical recommendations indicate the need for a biopsy of a metastatic focus in metastatic breast cancer (BC), but the optimal frequency of additional molecular analysis remains unclear. The discordance of hormonal receptors (HR) between the primary tumor and metastatic foci has prognostic...