Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9

• প্রধান লেখক: Koki Higashioka (লেখক), Noriko Koizumi (লেখক), Hidetoshi Sakurai (লেখক), Chie Sotozono (লেখক), Takahiko Sato (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Hindawi Limited, 2017-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

It is well known that myogenic regulatory factors encoded by the Myod1 family of genes have pivotal roles in myogenesis, with partially overlapping functions, as demonstrated for the mouse embryo. Myogenin-mutant mice, however, exhibit severe myogenic defects without compensation by other myogenic f...