Plasma triacylglycerols are biomarkers of β-cell function in mice and humans

• Main Authors: Ana Rodríguez Sánchez-Archidona (Author), Céline Cruciani-Guglielmacci (Author), Clara Roujeau (Author), Leonore Wigger (Author), Justine Lallement (Author), Jessica Denom (Author), Marko Barovic (Author), Nadim Kassis (Author), Florence Mehl (Author), Jurgen Weitz (Author), Marius Distler (Author), Christian Klose (Author), Kai Simons (Author), Mark Ibberson (Author), Michele Solimena (Author), Christophe Magnan (Author), Bernard Thorens (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: To find plasma biomarkers prognostic of type 2 diabetes, which could also inform on pancreatic β-cell deregulations or defects in the function of insulin target tissues. Methods: We conducted a systems biology approach to characterize the plasma lipidomes of C57Bl/6J, DBA/2J, and BALB/cJ...