First-in-human study to assess the pharmacokinetics, tolerability, and safety of single-dose oxybutynin hydrochloride administered via a microprocessor-controlled intravaginal ring

• Main Authors: Willem de Laat (Author), Lisa Pagan (Author), R. Karl Malcolm (Author), Maarten Wiegerinck (Author), Victor Nickolson (Author), Bertine Huisman (Author), Rik Stuurman (Author), Michiel van Esdonk (Author), Naomi Klarenbeek (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractPolymeric drug-releasing vaginal rings are useful for both local and systemic administration of drugs via the intravaginal route. Typically, they provide continuous sustained or controlled release of drug(s) over extended time periods, thereby avoiding overdose and improving adherence. This...