Development and validation of LC-MS/MS assay for the determination of Butoconazole in human plasma: Evaluation of systemic absorption following topical application in healthy volunteers

• मुख्य लेखकों: Eman G. Nouman (लेखक), Medhat A. Al-Ghobashy (लेखक), Hayam M. Lotfy (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Faculty of Pharmacy, Cairo University, 2017-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Butoconazole is an imidazole antifungal that is more effective than miconazole and clotrimazole for treatment of vaginal candidiasis. A highly sensitive tandem mass spectrometric assay was developed and validated to evaluate systemic absorption of Butoconazole following intravaginal administration....