IgG1 as a potential biomarker of post-chemotherapeutic relapse in visceral leishmaniasis, and adaptation to a rapid diagnostic test.

• Main Authors: Tapan Bhattacharyya (Author), Armon Ayandeh (Author), Andrew K Falconar (Author), Shyam Sundar (Author), Sayda El-Safi (Author), Marissa A Gripenberg (Author), Duncan E Bowes (Author), Caroline Thunissen (Author), Om Prakash Singh (Author), Rajiv Kumar (Author), Osman Ahmed (Author), Osama Eisa (Author), Alfarazdeg Saad (Author), Sara Silva Pereira (Author), Marleen Boelaert (Author), Pascal Mertens (Author), Michael A Miles (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Visceral leishmaniasis (VL), caused by protozoa of the Leishmania donovani complex, is a widespread parasitic disease of great public health importance; without effective chemotherapy symptomatic VL is usually fatal. Distinction of asymptomatic carriage from progressive disease and the p...