Protein-protein interaction-based high throughput screening for adenylyl cyclase 1 inhibitors: Design, implementation, and discovery of a novel chemotype

Genetic and preclinical studies have implicated adenylyl cyclase 1 (AC1) as a potential target for the treatment of chronic inflammatory pain. AC1 activity is increased following inflammatory pain stimuli and AC1 knockout mice show a marked reduction in responses to inflammatory pain. Previous drug...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tiffany S. Dwyer (Author), Joseph B. O'Brien (Author), Christopher P. Ptak (Author), Justin E. LaVigne (Author), Daniel P. Flaherty (Author), Val J. Watts (Author), David L. Roman (Author)
Formato: Livro
Publicado em: Frontiers Media S.A., 2022-09-01T00:00:00Z.
Assuntos:
Acesso em linha:Connect to this object online.
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Internet

Connect to this object online.

3rd Floor Main Library

Detalhes do Exemplar 3rd Floor Main Library
Área/Cota: A1234.567
Cód. Barras: 1 Disponível