Cholesterol 25-hydroxylase (CH25H) as a promoter of adipose tissue inflammation in obesity and diabetes

• Main Authors: Lucia Russo (Author), Lindsey Muir (Author), Lynn Geletka (Author), Jennifer Delproposto (Author), Nicki Baker (Author), Carmen Flesher (Author), Robert O'Rourke (Author), Carey N. Lumeng (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Expansion of visceral adipose tissue (VAT) and metabolic inflammation are consequences of obesity and associated with type 2 diabetes (T2DM). Metabolically activated adipose tissue macrophages (ATMs) undergo qualitative and quantitative changes that influence their inflammatory responses....