Carboxymethyl-Starch Excipients for Gastrointestinal Stable Oral Protein Formulations Containing Protease Inhibitors

• Main Authors: Patrick De Koninck (Author), Denis Archambault (Author), Francine Hamel (Author), Fathey Sarhan (Author), Mircea Alexandru Mateescu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2010-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. The aim of this study was to develop a formulation for bioactive compounds using Carboxymethyl Starch (CMS) as excipient containing protease inhibitors. This formulation provided gastro protection and enhanced stability against pancreatic enzymes. Such stability is needed for formulation of...