In vitro anti-Candida activity and single crystal X-ray structure of ({(1E)-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]amino}oxy)(4-nitrophenyl)methanone

• Main Authors: Mohamed I. Attia (Author), Hazem A. Ghabbour (Author), Azza S. Zakaria (Author), Hoong-Kun Fun (Author)
• Formato: Libro
• Publicado: Bangladesh Pharmacological Society, 2014-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Synthesis, characterization, and anti-Candida activity of ({(E)-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]amino}oxy)(4-nitrophenyl)methanone (4) are reported. Compound 4 showed anti-Candida albicans activity (MIC = 0.6862 µmol/mL) being nearly 5-fold more potent than the gold standard antifungal dru...