Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis.

• Auteurs principaux: Andrew A Voak (Auteur), Andy Harris (Auteur), Jose Miguel Coteron-Lopez (Auteur), Iñigo Angulo-Barturen (Auteur), Santiago Ferrer-Bazaga (Auteur), Simon L Croft (Auteur), Karin Seifert (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2021-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

<h4>Background</h4>There is a continued need to develop effective and safe treatments for visceral leishmaniasis (VL). Preclinical studies on pharmacokinetics and pharmacodynamics of anti-infective agents, such as anti-bacterials and anti-fungals, have provided valuable information in th...