Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis.

• Główni autorzy: Andrew A Voak (Autor), Andy Harris (Autor), Jose Miguel Coteron-Lopez (Autor), Iñigo Angulo-Barturen (Autor), Santiago Ferrer-Bazaga (Autor), Simon L Croft (Autor), Karin Seifert (Autor)
• Format: Książka
• Wydane: Public Library of Science (PLoS), 2021-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

<h4>Background</h4>There is a continued need to develop effective and safe treatments for visceral leishmaniasis (VL). Preclinical studies on pharmacokinetics and pharmacodynamics of anti-infective agents, such as anti-bacterials and anti-fungals, have provided valuable information in th...