Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis.

• Main Authors: Andrew A Voak (Author), Andy Harris (Author), Jose Miguel Coteron-Lopez (Author), Iñigo Angulo-Barturen (Author), Santiago Ferrer-Bazaga (Author), Simon L Croft (Author), Karin Seifert (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>There is a continued need to develop effective and safe treatments for visceral leishmaniasis (VL). Preclinical studies on pharmacokinetics and pharmacodynamics of anti-infective agents, such as anti-bacterials and anti-fungals, have provided valuable information in th...