S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis.

• Main Authors: Stefan J Frohberger (Author), Frederic Fercoq (Author), Anna-Lena Neumann (Author), Jayagopi Surendar (Author), Wiebke Stamminger (Author), Alexandra Ehrens (Author), Indulekha Karunakaran (Author), Estelle Remion (Author), Thomas Vogl (Author), Achim Hoerauf (Author), Coralie Martin (Author), Marc P Hübner (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neutrophils are essentially involved in protective immune responses against invading infective larvae of filarial nematodes. The present study investigated the impact of S100A8/S100A9 on protective immune responses against the rodent filarial nematode Litomosoides sigmodontis. S100A9 forms with S100...