Photochemical Treatment of Drosophila APCs Can Eliminate Associated Viruses and Maintain the APC Function for Generating Antigen-Specific CTLs Ex Vivo

• Main Authors: Jun Ye (Author), Chunxia Yang (Author), Zeling Cai (Author), Weixing Shi (Author), Hong Yu (Author)
• 格式: 图书
• 出版: Hindawi Limited, 2018-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Drosophila cells transfected with MHC class I and a number of costimulation molecules including B7.1, ICAM, LFA-3, and CD70 are potent antigen-presenting cells (APCs) for the generation of antigen-specific cytotoxic T cells (CTLs) in vitro. Using Drosophila APCs, CTLs specific for melanoma antigens...