Effects of Inonotus obliquus on ameliorating podocyte injury in ORG mice through TNF pathway and prediction of active compounds

• Main Authors: Zhaodi Han (Author), Le Gong (Author), Yani Xue (Author), Rui Wang (Author), Jing Liu (Author), Xinyu Wang (Author), Wenyan Zhao (Author), Hui Liao (Author), Rongshan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundPodocyte injury is a common pathologic mechanism in diabetic kidney disease (DKD) and obesity-related glomerulopathy (ORG). Our previous study confirmed that Inonotus obliquus (IO) improved podocyte injury on DKD rats. The current study explored the pharmacological effects, related mechani...