Drug-drug interactions of icenticaftor (QBW251) with a 5‐probe cytochrome P450 cocktail and oral contraceptives

Drug-drug interactions of icenticaftor (QBW251) with a 5‐probe cytochrome P450 cocktail and oral contraceptives

Abstract A drug-drug interaction (DDI) study was conducted to evaluate the effect of icenticaftor (QBW251) on the pharmacokinetics (PK) of a 5‐probe cytochrome P450 (CYP) substrate cocktail, guided by in vitro studies in human hepatocytes and liver microsomes. Another DDI study investigated the effe...

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Main Authors: Felix Huth (Author), Ulrike Glaenzel (Author), Anton Drollmann (Author), Wendy Weis (Author), Julia Zack (Author), Lidiya Bebrevska (Author)
Format: Book
Published: Wiley, 2024-09-01T00:00:00Z.
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