Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells

• Main Authors: Shadab Md (Author), Nabil A. Alhakamy (Author), Hibah M. Aldawsari (Author), Mohammad Husain (Author), Sabna Kotta (Author), Samaa T. Abdullah (Author), Usama A. Fahmy (Author), Mohamed A. Alfaleh (Author), Hani Z. Asfour (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Naringenin (NAR), a flavonoid mainly found in citrus and grapefruits, has proven anti-cancer activities. However, the poor water solubility and low bioavailability of NAR limits its use as a therapeutic agent. The aim of this study was to develop and optimize stable naringenin nanoemulsions (NAR-NE)...