Nucleolin recognizing silica nanoparticles inhibit cell proliferation by activating the Bax/Bcl-2/caspase-3 signalling pathway to induce apoptosis in liver cancer

• Glavni autori: Liangliang Xiang (Autor), Yun Li (Autor), Xinyu Gu (Autor), Shujie Li (Autor), Junwei Li (Autor), Jinlong Li (Autor), Yongxiang Yi (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Multifunctional nanocarrier platforms have shown great potential for the diagnosis and treatment of liver cancer. Here, a novel nucleolin-responsive nanoparticle platform was constructed for the concurrent detection of nucleolin and treatment of liver cancer. The incorporation of AS1411 aptamer, ica...