Clinical evaluation of the lot-to-lot consistency of an enterovirus 71 vaccine in a commercial-scale phase IV clinical trial

• Главные авторы: Jinhua Chen (Автор), Pengfei Jin (Автор), Xiaoqi Chen (Автор), Qunying Mao (Автор), Fanyue Meng (Автор), Xinguo Li (Автор), Wei Chen (Автор), Meizhi Du (Автор), Fan Gao (Автор), Pei Liu (Автор), Xiujuan Li (Автор), Changfu Guo (Автор), Tingbo Xie (Автор), Weiwei Lu (Автор), Qingliang Li (Автор), Li Li (Автор), Xing Yan (Автор), Xiang Guo (Автор), Hongqiao Du (Автор), Xiuling Li (Автор), Kai Duan (Автор), Fengcai Zhu (Автор)
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• Опубликовано: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• Предметы: article
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Objective To evaluate the immunogenicity, safety and lot-to-lot consistency of an inactivated enterovirus 71 (EV71) vaccine cultured in bioreactors with different specifications after full immunization. Methods A randomized, double-blind trial was performed in 3,000 children aged 6 ~ 35 months with...