Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation

• Main Authors: Sookyoung Jeon (Author), Eleonora Scorletti (Author), Joseph Dempsey (Author), Delfin Buyco (Author), Chelsea Lin (Author), Yedidya Saiman (Author), Susovon Bayen (Author), Julia Harkin (Author), Jasmin Martin (Author), Royce Hooks (Author), Besim Ogretmen (Author), Josepmaria Argemi (Author), Luma Melo (Author), Ramon Bataller (Author), Rotonya M. Carr (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Alcohol-associated liver disease (ALD) is the leading cause of liver-related mortality worldwide. Current strategies to manage ALD focus largely on advanced stage disease, however, metabolic changes such as glucose intolerance are apparent at the earliest stage of alcoholic steatosis and...