Model acetylcholinesterase‐Fc fusion glycoprotein biotechnology system for the manufacture of an organophosphorus toxicant bioscavenging countermeasure

• Main Authors: Thomas G. Biel (Author), Talia Faison (Author), Alicia M. Matthews (Author), Uriel Ortega‐Rodriguez (Author), Vincent M. Falkowski (Author), Edward Meek (Author), Xin Bush (Author), Matthew Flores (Author), Sarah Johnson (Author), Wells W. Wu (Author), Mari Lehtimaki (Author), Rong‐Fong Shen (Author), Cyrus Agarabi (Author), V. Ashutosh Rao (Author), Janice E. Chambers (Author), Tongzhong Ju (Author)
• Format: Book
• Published: Wiley, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Organophosphate (OP) toxicants remain an active threat to public health and to warfighters in the military. Current countermeasures require near immediate administration following OP exposure and are reported to have controversial efficacies. Acetylcholinesterase (AChE) fused to the human i...