Liquid chromatography-tandem mass spectrometric method for trace quantification of ethyl methanesulfonate: a genotoxic impurity in dapoxetine hydrochloride

• मुख्य लेखकों: Ravi Kiran Panchakarla (लेखक), Punna Rao Ravi (लेखक), Venkata Gowri Chandra Sekhar Kondapalli (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: SpringerOpen, 2021-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Dapoxetine hydrochloride is a selective serotonin reuptake inhibitor drug for treating premature ejaculation. This study was designed to develop and validate a sensitive and selective LC-MS/MS method for trace analysis of genotoxic impurity ethyl methanesulfonate in Dapoxetine hy...