Oxidative and glycolytic skeletal muscles deploy protective mechanisms to avoid atrophy under pathophysiological iron overload

• Main Authors: David Martin (Author), Kévin Nay (Author), François Robin (Author), Amélie Rebillard (Author), Luz Orfila (Author), Brice Martin (Author), Patricia Leroyer (Author), Pascal Guggenbuhl (Author), Suzanne Dufresne (Author), Philippe Noirez (Author), Martine Ropert (Author), Olivier Loréal (Author), Frédéric Derbré (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Iron excess has been proposed as an essential factor in skeletal muscle wasting. Studies have reported correlations between muscle iron accumulation and atrophy, either through ageing or by using experimental models of secondary iron overload. However, iron treatments performed i...