Pyrvinium Pamoate and Structural Analogs Are Early Macrofilaricide Leads

• Автори: Emma L. Gunderson (Автор), Clifford Bryant (Автор), Christina A. Bulman (Автор), Chelsea Fischer (Автор), Mona Luo (Автор), Ian Vogel (Автор), Kee-Chong Lim (Автор), Shabnam Jawahar (Автор), Nancy Tricoche (Автор), Denis Voronin (Автор), Christopher Corbo (Автор), Rene B. Ayiseh (Автор), Faustin P. T. Manfo (Автор), Glory E. Mbah (Автор), Fidelis Cho-Ngwa (Автор), Brenda Beerntsen (Автор), Adam R. Renslo (Автор), Sara Lustigman (Автор), Judy A. Sakanari (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-02-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Onchocerciasis and lymphatic filariasis are neglected tropical diseases caused by infection with filarial worms. Annual or biannual mass drug administration with microfilaricidal drugs that kill the microfilarial stages of the parasites has helped reduce infection rates and thus prevent transmission...