Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model

• Main Authors: Longlong Zhang (Author), Yuefei Zhu (Author), Xunbin Wei (Author), Xing Chen (Author), Yang Li (Author), Ying Zhu (Author), Jiaxuan Xia (Author), Yiheng Huang (Author), Yongzhuo Huang (Author), Jianxin Wang (Author), Zhiqing Pang (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Platelets buoy up cancer metastasis via arresting cancer cells, enhancing their adhesion, and facilitating their extravasation through the vasculature. When deprived of intracellular and granular contents, platelet decoys could prevent metastatic tumor formation. Inspired by these, we developed nano...