Anti-inflammatory effects of para-quinone methide derivatives on ulcerative colitis

• Main Authors: Yue Qiu (Author), Xin Li (Author), Xu Zhang (Author), Xiaotong Wang (Author), Xuekun Wang (Author), Jie Yang (Author), Guoyun Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of para-quinone methide derivatives were evaluated their anti-inflammatory activity. Through the screening of the lipopolysaccharide (LPS)-induced inflammatory cell model in Raw264.7 cells, it was found that the inhibitory activity of meta-substituted derivatives on NO production was superi...