Identification and functional analysis of variants of MYH6 gene promoter in isolated ventricular septal defects

• Main Authors: Ji-Yang Zuo (Author), Huan-Xin Chen (Author), Zhi-Gang Liu (Author), Qin Yang (Author), Guo-Wei He (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ventricular septal defect is the most common form of congenital heart diseases. MYH6 gene has a critical effect on the growth and development of the heart but the variants in the promoter of MYH6 is unknown. Patients and methods In 604 of the subjects (311 isolated and sporadic v...