Dual and selective inhibitors of pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate synthase (DHFR-TS) from Leishmania chagasi

• Κύριοι συγγραφείς: Bárbara Velame Ferreira Teixeira (Συγγραφέας), André Lacerda Braga Teles (Συγγραφέας), Suellen Gonçalves da Silva (Συγγραφέας), Camila Carane Bitencourt Brito (Συγγραφέας), Humberto Fonseca de Freitas (Συγγραφέας), Acássia Benjamim Leal Pires (Συγγραφέας), Thamires Quadros Froes (Συγγραφέας), Marcelo Santos Castilho (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Leishmaniasis is a tropical disease found in more than 90 countries. The drugs available to treat this disease have nonspecific action and high toxicity. In order to develop novel therapeutic alternatives to fight this ailment, pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate syn...