Modeling the catarrhal stage of Bordetella pertussis upper respiratory tract infections in mice

• Main Authors: Illiassou H. Soumana (Author), Kalyan K. Dewan (Author), Bodo Linz (Author), Israel Rivera (Author), Longhuan Ma (Author), Laura K. Howard (Author), Amanda D. Caulfield (Author), Colleen J. Sedney (Author), Uriel Blas-Machado (Author), Peter Sebo (Author), Eric T. Harvill (Author)
• Format: Book
• Published: The Company of Biologists, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pertussis (whooping cough) is a highly transmissible human respiratory disease caused by Bordetella pertussis, a human-restricted pathogen. Animal models generally involve pneumonic infections induced by depositing large numbers of bacteria in the lungs of mice. These models have informed us about t...