Safety, tolerability, and immunogenicity of a novel 4-antigen Staphylococcus aureus vaccine (SA4Ag) in healthy Japanese adults

• Main Authors: Megumi Inoue (Author), Takuma Yonemura (Author), James Baber (Author), Yasuko Shoji (Author), Masakazu Aizawa (Author), David Cooper (Author), Joseph Eiden (Author), William C. Gruber (Author), Kathrin U. Jansen (Author), Annaliesa S. Anderson (Author), Alejandra Gurtman (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A novel Staphylococcus aureus 4-antigen vaccine (SA4Ag) is under development, comprising capsular polysaccharide serotypes 5 and 8 (CP5 and CP8) conjugated to CRM197, recombinant protein clumping factor A (rmClfA), and recombinant manganese transporter protein C (MntC). We evaluated SA4Ag safety, to...