Daytime and outcomes after cardiac surgery: Systematic review and metaanalysis, insights from a large UK database review and post-hoc trial analysis

• Main Authors: Daniel Paul Fudulu (Author), Arnaldo Dimagli (Author), Lauren Dixon (Author), Manraj Sandhu (Author), Lucia Cocomello (Author), Gianni D Angelini (Author), Umberto Benedetto (Author)
• Format: Book
• Published: Elsevier, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Several studies have suggested a variation of myocardial tolerance to ischaemia depending on the daytime of surgery. To test this hypothesis, we conducted a three-level analysis: metaanalysis, national patient-level dataset analysis and a post-hoc trial analysis. Methods: We first perfor...