Metabolism of 2,3-Dehydrosilybin A and 2,3-Dehydrosilybin B: A Study with Human Hepatocytes and Recombinant UDP-Glucuronosyltransferases and Sulfotransferases

2,3-Dehydrosilybin A and 2,3-dehydrosilybin B are a pair of enantiomers formed by the oxidation of the natural flavonolignans silybin A and silybin B, respectively. However, the antioxidant activity of 2,3-dehydrosilybin molecules is much stronger than that of their precursors. Here, we investigated...

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Main Authors: Jiří Vrba (Author), Barbora Papoušková (Author), Kateřina Lněničková (Author), Pavel Kosina (Author), Vladimír Křen (Author), Jitka Ulrichová (Author)
Format: Book
Published: MDPI AG, 2021-06-01T00:00:00Z.
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