Computational Model of Antidepressant Response Heterogeneity as Multi-pathway Neuroadaptation

• Main Authors: Mariam B. Camacho (Author), Thomas J. Anastasio (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2017-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Current hypotheses cannot fully explain the clinically observed heterogeneity in antidepressant response. The therapeutic latency of antidepressants suggests that therapeutic outcomes are achieved not by the acute effects of the drugs, but rather by the homeostatic changes that occur as the brain ad...