In Silico Identification of Novel Inhibitors Targeting the Homodimeric Interface of Superoxide Dismutase from the Dental Pathogen <i>Streptococcus mutans</i>

• Main Authors: Carmen Cerchia (Author), Emanuela Roscetto (Author), Rosarita Nasso (Author), Maria Rosaria Catania (Author), Emmanuele De Vendittis (Author), Antonio Lavecchia (Author), Mariorosario Masullo (Author), Rosario Rullo (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The microaerophile <i>Streptococcus mutans</i>, the main microaerophile responsible for the development of dental plaque, has a single cambialistic superoxide dismutase (<i>Sm</i>SOD) for its protection against reactive oxygen species. In order to discover novel inhibitors of...