Exposure to Doxorubicin Modulates the Cardiac Response to Isoproterenol in Male and Female Mice

• Váldodahkkit: Kevin Agostinucci (Dahkki), Marianne K. O. Grant (Dahkki), Wongel Melaku (Dahkki), Chandini Nair (Dahkki), Beshay N. Zordoky (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2023-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Sex is a salient risk factor in the development of doxorubicin-induced cardiotoxicity. Sex differences in the heart's ability to respond to hypertrophic stimuli in doxorubicin-exposed animals have not been reported. We identified the sexual dimorphic effects of isoproterenol in mice pre-exposed...