The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor

The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor

G protein coupled receptor (GPCR) kinases (GRKs) are key regulators of GPCR signaling. Canonical mechanism of GPCR desensitization involves receptor phosphorylation by GRKs followed by arrestin recruitment and uncoupling from heterotrimeric G protein. Although β3-adrenergic receptor (β3AR) lacks pho...

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Main Authors: Emiliana Echeverría (Author), Maia Cabrera (Author), Valeria Burghi (Author), Máximo Sosa (Author), Sonia Ripoll (Author), Agustín Yaneff (Author), Federico Monczor (Author), Carlos Davio (Author), Carina Shayo (Author), Natalia Fernández (Author)
Format: Book
Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
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3rd Floor Main Library

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